Black Cohosh Root Extract – Black cohosh root extract has been extensively studied for its hormone balancing benefits during peri-menopause and menopause.

Trans-Resveratrol – Resveratrol, a polyphenol found in grapes and red wine, has been shown to have an effect on free radical scavenging and antioxidant properties in various tissues. Trans-resveratrol provides a range of supportive activities including hormonal balance and maintaining normal inflammatory balance.

Licorice Root Extract – Licorice root is a botanical used medicinally in both Western and Eastern cultures for several thousands of years, and is widely used today in Chinese medicine. The active components of licorice root include glycyrrhizin and isoflavones. Licorice root’s isoflavones have been shown to exert a balancing effect on estrogen levels.

Gamma Oryzanol – Gamma oryzanol (ferulic acid) is a natural compound extracted from rice bran oil. Gamma oryzanol was first shown to be effective for relieving hot flashes in the early 1960s. Numerous studies have highlighted the benefits of gamma oryzanol for menopausal complaints.

Dong Quai

Considered by many as the woman’s herb, Dong quai (Angelica sinensis) is native to China and Korea, where it is considered as a “female ginseng” due to its ability to reduce painful menstruation, support a regular and healthy menstrual cycle, and reduce menopausal symptoms, including hot flashes.

Acetyl L-carnitine (ALC) is an amino acid that is associated with increased energy production. It has been shown to increase the flow of free fatty acids, the fuel source for mitochondria,resulting in a significant boost in energy production. As women age, free radical production increases oxidative damage to the mitochondria, which can potentially decrease energy production. ALC has been shown to increase cellular energy (ATP) production and has been found, in combination with lipoic acid, to lower oxidative stress. Studies have also shown that ALC supports the immune response by protecting CD4 and CD8 immune cells and by supporting the reproduction of lymphocytes for the identification and elimination of invading antigens.

N-acetyl cysteine (NAC) is an antioxidant that scavenges free radicals and promotes liver detoxification. NAC has been shown to increase production of glutathione, an important antioxidant found in the body. In addition to its antioxidant activity, glutathione boosts the immune system by activating T-cells, helping to maintain immune balance.

Alpha lipoic acid (ALA) is a potent antioxidant and also plays a synergistic role in recharging other antioxidants such as vitamin C, vitamin E, CoQ10 and glutathione. Lipoic acid also plays a key role in detoxification. Studies have shown that a combination of ALA and acetyl L-carnitine helps minimize oxidative damage. Oxidative stress causes damage to DNA, RNA, proteins, mitochondrial membranes, and lipids and contributes to the functional decline of mitochondria, cells,tissues, and eventually organs such as the brain.

Resveratrol is a polyphenol molecule found in many plant species including grapes and cranberries and is found in high concentrations in wine. Polyphenols act as antioxidants that protect plants from damage that can be caused by bacteria, fungi, and radiation. Resveratrol is believed to be the dietary factor behind the “French Paradox” which is the high rate of cardiovascular wellness in the French population, despite their high fat intake. In addition to its antioxidant properties and support for cardiovascular function, resveratrol has been shown to support optimal immune function.

Broccoli seed extract contains a high amount of glucoraphanin, a compound that is a precursorto sulphoraphane. Sulphoraphane is a potent antioxidant in the body and also supports detoxification and immune response. Sulphoraphane has been shown to induce Phase II detoxification enzymes and raise intracellular glutathione levels.

Green tea polyphenols have demonstrated significant antioxidant, probiotic and immune supporting properties. The hydroxyl group of green tea polyphenols supports antioxidant activity by forming complexes with free radicals and neutralizing them, minimizing oxidative damage throughout the body. Green tea polyphenols also stimulate the activity of liver detoxification enzymes, promoting the detoxification of harmful chemicals out of the body.

Micronutrients – To increase cellular energy production efficiently, optimal levels of critical nutrients and enzyme cofactors must be achieved. MitoCleo is a multivitamin with an optimized backbone of vitamins and minerals necessary for increasing energy output and meeting daily nutritional needs.